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Laser zaps orthodontic pain in new trial

NCT ID NCT07651774

Symptom relief Sponsor: Foundation University Islamabad Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Aug 14, 2026 · Updated 3 times

Summary

This study tested whether a 635-nm low-level laser can reduce pain from orthodontic separators. Eighty healthy patients received laser on one side of the mouth and no treatment on the other. They rated spontaneous and chewing pain for 7 days. The goal is to see if this simple laser application can ease discomfort during braces treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
635-nm low-level laser therapy
What this could lead to
If effective, this could offer a simple, drug-free way to ease pain during orthodontic treatment.
What could go wrong
This is a small, completed trial. Results may not apply to all patients, and the effect may be modest or not clinically significant.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

80 people

The number who actually took part.

Started

Jun 2022

Finished

Jan 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

15 to 30 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Healthy and complete dentition including permanent second molars. * Good oral hygiene (absence of generalized calculus deposits assessed clinically). Exclusion Criteria: * Patients on pain killers or anti-inflammatory medication. * Spacing between molars and premolars. * History of diabetes mellitus, epilepsy or any other medical condition. * Ongoing periodontal disease. * Past history of orthodontic treatment.

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Conditions

The condition(s) this trial relates to.

Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chewing function Low level laser therapy Orthodontics Pain Visual analog scale

Contacts and locations

Locations

  • Foundation University Islamabad

    Islamabad, Federal, 44000, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.