Laser light may soothe chemo mouth pain in kids
NCT ID NCT02604329
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether a low-level laser can be used to treat painful mouth sores caused by chemotherapy or radiation in children with cancer. The laser was applied to the inside of the mouth every two days while sores were present. The main goal was to see if the treatment could be given at least three times in the first week. Only 22 children took part, and the study did not compare the laser to any other treatment, so it cannot say if the laser actually helps.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- low-level laser therapy (Oncolase Digi device)
- What this could lead to
- If this approach works, it could offer a non-drug way to ease mouth sore pain and speed healing in children undergoing cancer treatment.
- What could go wrong
- This is a very small feasibility study (22 children) with no control group, so it cannot prove effectiveness. The procedure may be difficult to apply consistently in young, sick children.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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22 people
The number who actually took part.
- Started
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Dec 2015
- Finished
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Feb 2017
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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3 to 16 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Hospitalization in the oncology ward of the university hospital Toulouse France * Onco-haematological paediatric patients treated by radio- and /or chemo-therapy, affected by an oral mucositis of WHO grade 2 to 4, * lack of any physical or psychological disease which could interfere with the realization of the study. Exclusion Criteria: * Onco-haematological paediatric patients treated by radio- and /or chemo-therapy, affected by an oral mucositis of WHO's grade under 2 * Child suffering from epilepsy * Patient wearing a cardiac pacemaker * Patient not able to open their mouth at least 20 mm * Patient refusing the wearing of safety goggles.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
UH Toulouse
Toulouse, 31059, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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