Laser and surgery combo may speed up braces, protect teeth
NCT ID NCT07442825
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether using a low-level laser along with a small gum surgery (called piezocision) can safely speed up moving front teeth back in people with overbite. 66 healthy patients aged 17-28 were split into three groups: laser plus surgery, surgery alone, or standard braces. The researchers measured root shortening and gum health on X-rays and exams to see if the combo is safer and faster.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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66 people
The number who actually took part.
- Started
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May 2023
- Finished
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Mar 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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17 to 28 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Healthy patients aged 17-28 years. 2. Diagnosed with a Class II division 1 malocclusion, indicated for extraction of the upper first premolars, with an overjet of 4-10 mm and a normal or increased facial height assessed clinically and cephalometrically using three angles (MM= 23ᵒ-33ᵒ, Jarabak Ratio ≤ 64%, and Y-axis angle= 66ᵒ-75ᵒ) 3. A skeletal Class II relationship, confirmed by a cephalometric ANB angle between 4° and 7° 4. An overbite of 0%-33% 5. Good oral hygiene, defined by a probing depth of ≤3 mm and no radiographic evidence of alveolar bone loss 6. Absence or a mild level of crowding 7. A full complement of teeth, excluding third molars. Exclusion Criteria: 1. A history of previous orthodontic treatment 2. Any systemic disease or medication known to interfere with orthodontic tooth movement. 3. Congenitally missing or extracted teeth in the maxilla (except third molars) 4. Poor oral hygiene, 5. Active periodontal disease (probing depth ≥4 mm, radiographic bone loss, gingival index \>1, plaque index \>1) 6. Moderate to severe maxillary crowding (Little's Irregularity Index ≥4).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Orthodontics Department, Faculty of Dentistry
Damascus, Syrian Arab Republic, DM20AM19, Syria
More trials for these conditions
Other studies related to the condition(s) this trial covers.