Laser heat therapy could ease knee pain without smoke
NCT ID NCT07423182
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding a special laser treatment (CO2 infrared laser moxibustion) to standard exercise can reduce knee pain and improve movement in people with knee osteoarthritis. About 68 adults aged 55-65 with knee arthritis will receive either exercise alone or exercise plus the laser treatment over 8 weeks. Researchers will measure pain, knee motion, and cartilage changes at 3 and 6 months to see if the laser provides extra relief.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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68 people
The number who actually took part.
- Started
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Oct 2025
- Expected to finish
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Jul 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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55 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria Adults aged 55 to 65 years, male or female. Diagnosis of knee osteoarthritis with radiographic evidence (Kellgren-Lawrence grade 2 or higher). Knee osteoarthritis grade II or III according to the American Rheumatism Association (ARA) classification criteria. History of moderate to severe knee pain on most days during the past month. Able and willing to provide written informed consent and comply with study procedures. Exclusion Criteria Other diseases affecting the knee, such as rheumatoid arthritis, ankylosing spondylitis, fibromyalgia syndrome, or chronic fatigue syndrome. Use of steroid medication or acupuncture or moxibustion treatment within the previous 3 months. Intra-articular hyaluronate injection within the previous 6 months. Arthrocentesis or arthroscopy within the previous 1 year. Knee or hip replacement surgery, or planned joint replacement surgery during the trial period. Use of other external treatments during the trial (e.g., topical medication for knee pain). Body mass index (BMI) greater than 30 kg/m². Lower-limb fracture or injury affecting function. Neurological disorders or nerve root compression affecting the lower limb.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Rashid Latif Medical College, Lahore, Pakistan
Lahore, 54000, Pakistan
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Other studies related to the condition(s) this trial covers.
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