New combo therapy aims to ease stubborn back pain without drugs
NCT ID NCT07556926
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study will test whether adding high-intensity laser therapy to a hands-on technique called Mulligan mobilization can reduce pain and improve movement in people with chronic low back pain. Fifty adults aged 18-60 will be split into two groups: one gets the combo treatment, the other gets mobilization alone. The goal is to see if the combination works better for pain, disability, and range of motion.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- High-intensity laser therapy and Mulligan mobilization
- What this could lead to
- If it works, this could point toward a more effective non-drug treatment for chronic low back pain.
- What could go wrong
- This is a small pilot study (50 people) that hasn't started yet, so results are uncertain. The combined approach may not prove better than mobilization alone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Apr 2026
An estimate. Start dates often move.
- Expected to finish
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Jun 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male and female participants aged 18-60 years * Diagnosis of chronic non-specific low back pain (pain persisting for ≥3 months) * Pain localized between the lower costal margins and gluteal folds, with or without referred pain * Baseline pain intensity of ≥3 on the Numeric Pain Rating Scale (NPRS) * Ability to understand and follow instructions and provide informed consent * Not currently receiving other forms of physiotherapy or structured treatment for low back pain during the study period Exclusion Criteria: * Specific spinal pathology (e.g., fracture, tumor, infection, inflammatory diseases such as ankylosing spondylitis) * History of spinal surgery * Neurological deficits or signs of nerve root compression (e.g., severe radiculopathy) * Pregnancy * Severe osteoporosis or other contraindications to manual therapy * Contraindications to high-intensity laser therapy (e.g., malignancy in the treatment area, photosensitivity disorders) * Current use of medications that significantly affect pain perception (e.g., high-dose opioids) * Participation in another clinical trial within the last 3 months
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Middle East University
Amman, Jordan
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Other studies related to the condition(s) this trial covers.
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