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New program aims to zap away stress with nerve stimulation and breathing

NCT ID NCT07498881

Symptom relief Sponsor: University of the Basque Country (UPV/EHU) Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a 5-day program called LasaiOn that combines mild nerve stimulation with breathing exercises to help adults feel less stressed and anxious. Researchers will measure changes in mood, heart rate, and brain activity in 200 participants. The goal is to see if this safe, non-drug approach can improve emotional well-being.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 200 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Mar 2026

An estimate. Start dates often move.

Expected to finish

Mar 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Ability to provide written informed consent * Physically healthy, with no relevant uncontrolled medical condition * Availability to complete the 5-day study protocol (1 session/day), including baseline and post-intervention assessments * Intact external ear and suitability for electrode placement on the tragus and acquisition of study recordings (EEG, EDA, HRV) Exclusion Criteria: * History of cardiovascular disease, diabetes, or hypertension * Severe bradycardia * Active implanted electronic device (e.g., pacemaker, cochlear implant, neurostimulator) * History of vagus nerve transection surgery (cervical vagotomy) * Pregnancy * Current or past clinically significant psychiatric disorder * Current or past clinically significant neurological disorder * Use of CNS-active medication * Substance misuse, including nicotine or alcohol * Dermatitis, infection, or lesions of the ear that could interfere with electrode application * Ongoing treatment with medications that modulate autonomic nervous system activity or may alter psychophysiological measures (e.g., HRV, EDA, EEG)

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Adult

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Euskal Herriko Unibertsitatea

    San Sebastián, Gipuzkoa, 20018, Spain

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