Ultrasound may help doctors decide when to remove breathing tubes
NCT ID NCT07523828
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at 100 ICU patients who are ready to try breathing on their own after being on a ventilator. It compares two methods to check for throat swelling (laryngeal edema): the standard cuff leak test and a newer ultrasound technique. The goal is to see if ultrasound can better predict who will successfully come off the ventilator without complications like stridor or sore throat.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to a better, non-invasive way to predict which ICU patients are ready to come off the breathing tube, reducing complications.
- What could go wrong
- This is an early observational study with only 100 participants, so results may not apply to all ICU patients. The measurements may not be accurate enough to change practice.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Apr 2026
An estimate. Start dates often move.
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population will consist of intensive care patients over the age of 18 who are followed up with mechanical ventilation support and intubation for at least 24 hours at the Anesthesiology and Reanimation Clinic of Fatih Sultan Mehmet Training and Research Hospital and who have given informed consent by their guardian or parent.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients who have been intubated and receiving invasive mechanical ventilation for at least 24 hours in the Intensive Care Unit of Fatih Sultan Mehmet Training and Research Hospital and who are considered by the intensive care physician to be ready for weaning from mechanical ventilation: * Patients over 18 years of age * Patients who have given their voluntary consent Exclusion Criteria: * Patients under 18 years of age * Patients with a history of oral cavity surgery such as direct laryngoscopy and biopsy, microlaryngoscopic surgery, tonsillectomy, adenoidectomy, soft palate, oropharynx, hypopharynx, larynx and trachea, * Patients with a history of allergy, asthma, reflux, upper respiratory tract viral or fungal infections, and cancer surgery, * Patients who received radiotherapy to the neck region, or who had more than one intubation attempt in the previous year, * Tracheostomized patients, patients with upper respiratory tract obstruction, vocal cord paralysis, and patients with stridor clinical picture before intubation, * Patients for whom voluntary consent cannot be obtained
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Fatih Sultan Mehmet Training and Research Hospital
Istanbul, Ataşehir, 34752, Turkey (Türkiye)
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