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New hope for rare cancers: targeted drug shrinks tumors in Gene-Matched patients

NCT ID NCT06390852

First seen Sep 30, 2025 · Last updated May 01, 2026 · Updated 23 times

Summary

This study tests a drug called larotrectinib in people with advanced cancers that have a specific genetic change called an NTRK fusion. The drug blocks a faulty protein that helps cancer grow. About 35 adults with various solid tumors or lymphomas will receive the drug to see if their tumors shrink or stop growing.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • ECOG-ACRIN Cancer Research Group

    Philadelphia, Pennsylvania, 19103, United States

Conditions

Explore the condition pages connected to this study.