Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

New cholesterol combo pill aims to slash bad cholesterol without prior meds

NCT ID NCT07619131

Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Sep 11, 2026 · Updated 2 times

Summary

This study tests a new pill that combines two drugs (laroprovstat and rosuvastatin) to lower LDL or 'bad' cholesterol. About 600 adults with high cholesterol who have never taken cholesterol-lowering medication will receive either the combination, one of the drugs alone, or a placebo. The main goal is to see how much LDL drops after 8 weeks and to check for side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

About 600 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2026

Expected to finish

Jul 2027

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 130 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participant must be ≥ 18 years of age * Participants with no clinical history of atherosclerotic cardiovascular disease (ASCVD) and a 10-year ASCVD risk estimated as low * Participants who have not received any LLT in the 3 months prior to screening Exclusion Criteria: * Asian origin. * Statin intolerance * Uncontrolled severe hypertension * Uncontrolled type 2 diabetes mellitus * Inadequately treated hypothyroidism

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Hypercholesterolaemia are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

Hypercholesterolemia hypercholesterolemia, familial, 1 hyperlipidemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hypercholesterolaemia

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    152 sites in 11 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Research Site

    NOT_YET_RECRUITING

    Dothan, Alabama, 36305, United States

  • Research Site

    NOT_YET_RECRUITING

    Chandler, Arizona, 85225, United States

  • Research Site

    NOT_YET_RECRUITING

    Phoenix, Arizona, 85053, United States

  • Research Site

    NOT_YET_RECRUITING

    Huntington Beach, California, 92647, United States

  • Research Site

    NOT_YET_RECRUITING

    Loma Linda, California, 92354, United States

  • Research Site

    NOT_YET_RECRUITING

    Lomita, California, 90717, United States

  • Research Site

    NOT_YET_RECRUITING

    Long Beach, California, 90815, United States

  • Research Site

    NOT_YET_RECRUITING

    San Dimas, California, 91773, United States

  • Research Site

    NOT_YET_RECRUITING

    Arvada, Colorado, 80002, United States

  • Research Site

    RECRUITING

    Colorado Springs, Colorado, 80909, United States

  • Research Site

    NOT_YET_RECRUITING

    Waterbury, Connecticut, 06708, United States

  • Research Site

    NOT_YET_RECRUITING

    Clearwater, Florida, 33765, United States

  • Research Site

    NOT_YET_RECRUITING

    DeLand, Florida, 32720, United States

  • Research Site

    NOT_YET_RECRUITING

    Hollywood, Florida, 33021, United States

  • Research Site

    NOT_YET_RECRUITING

    Jacksonville, Florida, 32209, United States

  • Research Site

    RECRUITING

    Lakeland, Florida, 33813, United States

  • Research Site

    NOT_YET_RECRUITING

    Miami Lakes, Florida, 33016, United States

  • Research Site

    NOT_YET_RECRUITING

    Ocoee, Florida, 34761, United States

  • Research Site

    NOT_YET_RECRUITING

    Plantation, Florida, 33324, United States

  • Research Site

    NOT_YET_RECRUITING

    Port Orange, Florida, 32127, United States

  • Research Site

    NOT_YET_RECRUITING

    Tampa, Florida, 33606, United States

  • Research Site

    NOT_YET_RECRUITING

    Atlanta, Georgia, 30303, United States

  • Research Site

    RECRUITING

    Conyers, Georgia, 30094, United States

  • Research Site

    NOT_YET_RECRUITING

    Decatur, Georgia, 30030, United States

  • Research Site

    RECRUITING

    Hinesville, Georgia, 31313, United States

  • Research Site

    NOT_YET_RECRUITING

    Peachtree Corners, Georgia, 30092, United States

  • Research Site

    NOT_YET_RECRUITING

    Champaign, Illinois, 61822, United States

  • Research Site

    NOT_YET_RECRUITING

    Chicago, Illinois, 60607, United States

  • Research Site

    NOT_YET_RECRUITING

    Chicago, Illinois, 60640, United States

  • Research Site

    NOT_YET_RECRUITING

    Island Lake, Illinois, 60042, United States

  • Research Site

    NOT_YET_RECRUITING

    Melrose Park, Illinois, 60160, United States

  • Research Site

    NOT_YET_RECRUITING

    Palos Hills, Illinois, 60465, United States

  • Research Site

    NOT_YET_RECRUITING

    Evansville, Indiana, 47714, United States

  • Research Site

    NOT_YET_RECRUITING

    Waterloo, Iowa, 50701, United States

  • Research Site

    NOT_YET_RECRUITING

    Derby, Kansas, 67037, United States

  • Research Site

    RECRUITING

    Lexington, Kentucky, 40503, United States

  • Research Site

    NOT_YET_RECRUITING

    Louisville, Kentucky, 40205, United States

  • Research Site

    NOT_YET_RECRUITING

    Zachary, Louisiana, 70791, United States

  • Research Site

    NOT_YET_RECRUITING

    Annapolis, Maryland, 21401, United States

  • Research Site

    NOT_YET_RECRUITING

    Beltsville, Maryland, 20705, United States

  • Research Site

    NOT_YET_RECRUITING

    Bowie, Maryland, 20715, United States

  • Research Site

    NOT_YET_RECRUITING

    Lutherville-Timonium, Maryland, 21093, United States

  • Research Site

    NOT_YET_RECRUITING

    Oxon Hill, Maryland, 20745, United States

  • Research Site

    NOT_YET_RECRUITING

    Flint, Michigan, 48503, United States

  • Research Site

    NOT_YET_RECRUITING

    Troy, Michigan, 48098, United States

  • Research Site

    NOT_YET_RECRUITING

    Kansas City, Missouri, 64108, United States

  • Research Site

    NOT_YET_RECRUITING

    St Louis, Missouri, 63110, United States

  • Research Site

    NOT_YET_RECRUITING

    St Louis, Missouri, 63136, United States

  • Research Site

    RECRUITING

    Millville, New Jersey, 08332, United States

  • Research Site

    NOT_YET_RECRUITING

    Astoria, New York, 11106, United States

  • Research Site

    NOT_YET_RECRUITING

    Brooklyn, New York, 11201, United States

  • Research Site

    NOT_YET_RECRUITING

    Brooklyn, New York, 11220, United States

  • Research Site

    NOT_YET_RECRUITING

    The Bronx, New York, 10455, United States

  • Research Site

    NOT_YET_RECRUITING

    Durham, North Carolina, 27705, United States

  • Research Site

    NOT_YET_RECRUITING

    Morehead City, North Carolina, 28557, United States

  • Research Site

    NOT_YET_RECRUITING

    Statesville, North Carolina, 28625, United States

  • Research Site

    NOT_YET_RECRUITING

    Wilmington, North Carolina, 28401, United States

  • Research Site

    NOT_YET_RECRUITING

    Winston-Salem, North Carolina, 27157, United States

  • Research Site

    NOT_YET_RECRUITING

    Columbus, Ohio, 43213, United States

  • Research Site

    NOT_YET_RECRUITING

    Dayton, Ohio, 45424, United States

  • Research Site

    NOT_YET_RECRUITING

    Tulsa, Oklahoma, 74137, United States

  • Research Site

    NOT_YET_RECRUITING

    Portland, Oregon, 97223, United States

  • Research Site

    NOT_YET_RECRUITING

    Newport, Pennsylvania, 17074, United States

  • Research Site

    NOT_YET_RECRUITING

    Smithfield, Pennsylvania, 15478, United States

  • Research Site

    NOT_YET_RECRUITING

    Anderson, South Carolina, 29621, United States

  • Research Site

    NOT_YET_RECRUITING

    Knoxville, Tennessee, 37938, United States

  • Research Site

    NOT_YET_RECRUITING

    Houston, Texas, 77002, United States

  • Research Site

    NOT_YET_RECRUITING

    Houston, Texas, 77087, United States

  • Research Site

    NOT_YET_RECRUITING

    Houston, Texas, 77099, United States

  • Research Site

    NOT_YET_RECRUITING

    San Antonio, Texas, 78231, United States

  • Research Site

    NOT_YET_RECRUITING

    Tomball, Texas, 77375, United States

  • Research Site

    NOT_YET_RECRUITING

    Victoria, Texas, 77901, United States

  • Research Site

    NOT_YET_RECRUITING

    Layton, Utah, 84041, United States

  • Research Site

    RECRUITING

    Salt Lake City, Utah, 84109, United States

  • Research Site

    RECRUITING

    South Jordan, Utah, 84095, United States

  • Research Site

    NOT_YET_RECRUITING

    Richmond, Virginia, 23219, United States

  • Research Site

    NOT_YET_RECRUITING

    Redmond, Washington, 98052, United States

  • Research Site

    NOT_YET_RECRUITING

    Burgas, 8000, Bulgaria

  • Research Site

    NOT_YET_RECRUITING

    Plovdiv, 4002, Bulgaria

  • Research Site

    NOT_YET_RECRUITING

    Razgrad, 7200, Bulgaria

  • Research Site

    NOT_YET_RECRUITING

    Sevlievo, 5400, Bulgaria

  • Research Site

    NOT_YET_RECRUITING

    Sofia, 1202, Bulgaria

  • Research Site

    NOT_YET_RECRUITING

    Sofia, 1431, Bulgaria

  • Research Site

    NOT_YET_RECRUITING

    Sofia, 1527, Bulgaria

  • Research Site

    NOT_YET_RECRUITING

    Varna, 9010, Bulgaria

  • Research Site

    NOT_YET_RECRUITING

    Veliko Tarnovo, 5006, Bulgaria

  • Research Site

    RECRUITING

    Hamilton, Ontario, L8L 5G4, Canada

  • Research Site

    RECRUITING

    Scarborough Village, Ontario, M1R 0B1, Canada

  • Research Site

    RECRUITING

    Stouffville, Ontario, L4A1H2, Canada

  • Research Site

    NOT_YET_RECRUITING

    Chicoutimi, Quebec, G7H 7K9, Canada

  • Research Site

    RECRUITING

    Sherbrooke, Quebec, J1J 2G2, Canada

  • Research Site

    NOT_YET_RECRUITING

    Victoriaville, Quebec, G6P 3Z8, Canada

  • Research Site

    NOT_YET_RECRUITING

    Aarhus, 8200, Denmark

  • Research Site

    NOT_YET_RECRUITING

    Copenhagen, 2400, Denmark

  • Research Site

    NOT_YET_RECRUITING

    Gandrup, 9362, Denmark

  • Research Site

    NOT_YET_RECRUITING

    Herlev, 2730, Denmark

  • Research Site

    NOT_YET_RECRUITING

    Herning, 7400, Denmark

  • Research Site

    NOT_YET_RECRUITING

    Svendborg, 5700, Denmark

  • Research Site

    NOT_YET_RECRUITING

    Vejle, 7100, Denmark

  • Research Site

    NOT_YET_RECRUITING

    Viborg, 8800, Denmark

  • Research Site

    NOT_YET_RECRUITING

    Ahrensburg, 22926, Germany

  • Research Site

    NOT_YET_RECRUITING

    Berlin, 10787, Germany

  • Research Site

    NOT_YET_RECRUITING

    Bochum, 44789, Germany

  • Research Site

    NOT_YET_RECRUITING

    Gladbeck, 45968, Germany

  • Research Site

    NOT_YET_RECRUITING

    Hamburg, 20095, Germany

  • Research Site

    NOT_YET_RECRUITING

    Hanover, 30449, Germany

  • Research Site

    NOT_YET_RECRUITING

    Karlsruhe, 76137, Germany

  • Research Site

    NOT_YET_RECRUITING

    Leipzig, 04177, Germany

  • Research Site

    NOT_YET_RECRUITING

    Löhne, 32584, Germany

  • Research Site

    NOT_YET_RECRUITING

    Magdeburg, 39110, Germany

  • Research Site

    NOT_YET_RECRUITING

    Obertshausen, 63179, Germany

  • Research Site

    NOT_YET_RECRUITING

    Wiesbaden, 65189, Germany

  • Research Site

    NOT_YET_RECRUITING

    Budapest, 1027, Hungary

  • Research Site

    NOT_YET_RECRUITING

    Budapest, 1036, Hungary

  • Research Site

    NOT_YET_RECRUITING

    Budapest, 1138, Hungary

  • Research Site

    NOT_YET_RECRUITING

    Kaposvár, 7400, Hungary

  • Research Site

    NOT_YET_RECRUITING

    Zalaegerszeg, 8900, Hungary

  • Research Site

    NOT_YET_RECRUITING

    Haifa, 3109601, Israel

  • Research Site

    NOT_YET_RECRUITING

    Jerusalem, 9103102, Israel

  • Research Site

    NOT_YET_RECRUITING

    Jerusalem, 91120, Israel

  • Research Site

    NOT_YET_RECRUITING

    Kfar Saba, 4428164, Israel

  • Research Site

    NOT_YET_RECRUITING

    Petah Tikva, 49100, Israel

  • Research Site

    NOT_YET_RECRUITING

    Częstochowa, 42-217, Poland

  • Research Site

    SUSPENDED

    Gdynia, 81-384, Poland

  • Research Site

    NOT_YET_RECRUITING

    Katowice, 40-772, Poland

  • Research Site

    SUSPENDED

    Lodz, 91-363, Poland

  • Research Site

    NOT_YET_RECRUITING

    Lodz, 93-338, Poland

  • Research Site

    NOT_YET_RECRUITING

    Lublin, 20-011, Poland

  • Research Site

    NOT_YET_RECRUITING

    Lublin, 20-718, Poland

  • Research Site

    NOT_YET_RECRUITING

    Warsaw, 00-719, Poland

  • Research Site

    NOT_YET_RECRUITING

    Warsaw, 02-758, Poland

  • Research Site

    NOT_YET_RECRUITING

    Barcelona, 08025, Spain

  • Research Site

    NOT_YET_RECRUITING

    Barcelona, 08540, Spain

  • Research Site

    NOT_YET_RECRUITING

    Barcelona, 08902, Spain

  • Research Site

    NOT_YET_RECRUITING

    Figueres, 17600, Spain

  • Research Site

    NOT_YET_RECRUITING

    La Roca del Vallès, 08430, Spain

  • Research Site

    NOT_YET_RECRUITING

    Mataró, 08303, Spain

  • Research Site

    NOT_YET_RECRUITING

    Viladecans, 08840, Spain

  • Research Site

    NOT_YET_RECRUITING

    Ivano-Frankivsk, 76018, Ukraine

  • Research Site

    NOT_YET_RECRUITING

    Kyiv, 02002, Ukraine

  • Research Site

    NOT_YET_RECRUITING

    Kyiv, 03037, Ukraine

  • Research Site

    NOT_YET_RECRUITING

    Kyiv, 03049, Ukraine

  • Research Site

    NOT_YET_RECRUITING

    Kyiv, 04114, Ukraine

  • Research Site

    NOT_YET_RECRUITING

    Kyiv, 04210, Ukraine

  • Research Site

    NOT_YET_RECRUITING

    Lviv, 79016, Ukraine

  • Research Site

    NOT_YET_RECRUITING

    Uzhhorod, 88014, Ukraine

  • Research Site

    NOT_YET_RECRUITING

    Coventry, CV3 4FJ, United Kingdom

  • Research Site

    NOT_YET_RECRUITING

    Knutsford, WA16 9DX, United Kingdom

  • Research Site

    NOT_YET_RECRUITING

    London, W6 7HY, United Kingdom

  • Research Site

    NOT_YET_RECRUITING

    Orpington, BR5 3QG, United Kingdom

  • Research Site

    NOT_YET_RECRUITING

    Poole, BH14 8EE, United Kingdom

  • Research Site

    NOT_YET_RECRUITING

    Shipley, BD18 3SA, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.