Can a simple heart rate drug prevent Surgery-Related heart attacks?
NCT ID NCT07168421
First seen Nov 01, 2025 · Last updated Jun 20, 2026 · Updated 39 times
Summary
This study tests whether the drug landiolol can safely keep heart rate below 90 beats per minute during major surgery in 114 patients at risk for heart problems. The goal is to see if this approach is feasible and might reduce heart injury after surgery. Participants receive landiolol continuously during and after surgery, with the dose adjusted to maintain the target heart rate.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CARDIOVASCULAR (CV) RISK are added.
Genom att skicka in godkänner du våra Användarvillkor
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
Genom att skicka in godkänner du våra Användarvillkor
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Bern University Hospital, Freiburgstrasse
RECRUITINGBern, 3010, Switzerland
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Landiolol (a short-acting beta-blocker given intravenously)
What this could lead to
If successful, this could show that controlling heart rate during surgery is feasible and may reduce heart damage in high-risk patients.
What could go wrong
This is a small feasibility trial, not designed to prove the drug prevents heart injury. The heart rate target may not be achievable or may cause side effects like low blood pressure.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.