Simple swab may predict labor success for First-Time moms
NCT ID NCT07637318
First seen Jun 27, 2026 · Last updated Jul 21, 2026 · Updated 2 times
Summary
This study looks at whether certain natural chemicals in vaginal fluid can predict if labor induction will work in first-time mothers. Researchers will collect a swab from 190 women before induction and track whether they go into active labor. The goal is to find a way to avoid failed inductions and reduce C-sections.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to a simple test that helps doctors know when labor induction is likely to work, reducing unnecessary C-sections.
- What could go wrong
- This is an early observational study with only 190 participants, so results may not apply to all women. The biomarkers may not reliably predict outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 190 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jun 2026
An estimate. Start dates often move.
- Expected to finish
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Jan 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Nulliparous patients
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 18 years * Singleton pregnancy * Gestational age ≥ 39 weeks * Nulliparous * Live foetus * Cephalic presentation * Intact membranes * Bishop score \< 6 * Willing to participate in the study Exclusion Criteria * A minor or a protected adult (under guardianship or conservatorship) * Individuals who don't speak French or are not accompanied by a third party who speaks French * Suspected intrauterine fetal growth restriction (estimated fetal weight \< 3rd percentile or \< 10th percentile with abnormal fetal Doppler) * Presence of fetal malformations and/or genetic or chromosomal abnormalities
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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AP-HP - Hôpital Cochin - Maternité Port-Royal
Paris, Île-de-France Region, 75014, France