New combo procedure aims to cut stroke risk and improve heart function in AFib patients

NCT ID NCT07453940

Recruiting now Disease control Sponsor: Sir Run Run Shaw Hospital Source: ClinicalTrials.gov ↗

First seen Mar 22, 2026 · Last updated May 24, 2026 · Updated 4 times

Summary

This study compares two approaches for people with persistent atrial fibrillation (a type of irregular heartbeat) who have mild symptoms but a high risk of stroke. One group gets a procedure to close off a part of the heart called the left atrial appendage (LAAC), while the other group gets that plus a newer type of ablation (PFA) to correct the heart rhythm. The goal is to see if the combined treatment improves exercise capacity and brain blood flow more than closure alone. About 50 adults will take part, and their progress will be tracked for 6 months.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Sir Run Run Shaw Hospital
RECRUITING

Hangzhou, Zhejiang, 310000, China

Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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ATRIAL APPENDAGE CLOSURE FOR ATRIAL FIBRILLATION PFA ABLATION AND LAAC PROCEDURES