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New device seals Stroke-Causing heart pouch during bypass surgery

NCT ID NCT07360899

First seen Jan 23, 2026 · Last updated Jun 22, 2026 · Updated 21 times

Summary

This study tests a device called AtriLASH that closes a small heart pouch (the left atrial appendage) during planned heart surgery in 200 people with atrial fibrillation. The goal is to prevent blood clots that cause strokes, potentially reducing the need for blood-thinning medications. Researchers will check if the pouch stays closed after 3 months and track any strokes or bleeding events.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Institute of cardiovascular diseases Vojvodina

    RECRUITING

    Kamenitz, Vojvodina, 21204, Serbia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

AtriLASH device (suture-based closure device made of Seralene material)

What this could lead to

If successful, this could offer a safer way to reduce stroke risk in atrial fibrillation patients undergoing heart surgery, potentially allowing some to stop long-term blood thinners.

What could go wrong

This is a single-arm study with no comparison group, so benefits are uncertain. The device may not fully close the appendage, and risks like bleeding or embolism remain. Long-term stroke reduction is not yet proven.

Conditions

The condition(s) this trial relates to.

atrial fibrillation stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.