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Simple supplement and exercise combo may boost aging brains

NCT ID NCT07466290

Knowledge-focused Sponsor: University of Vienna Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether taking L-serine (an amino acid) with or without strength training can improve memory, thinking, and physical fitness in healthy adults aged 65 to 85. Over 48 weeks, participants will take either a placebo, L-serine, or L-serine plus strength training. The goal is to learn how diet and exercise support healthy aging.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 126 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Mar 2026

An estimate. Start dates often move.

Expected to finish

Dec 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

65 to 85 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Men and women between the ages of 65 and 85 * Mini-Mental-State \>23 * Independently mobile, without aids (walker, cane, etc.) Exclusion Criteria: * Chronic diseases that contraindicate medical training therapy * Regular strength training (\>1x/week) in the last 6 months before confinement * Frailty Index ≥ 3 * Lack of written consent to test physical performance * Regular use of Cortison-containing medications or Antibiotika * MR-specific exclusion criteria: claustrophobia, metal equipment or other magnetic Material in or on the body * Non-compliance with the study protocol: \<70% of the planned L-serine administration, \<70% of the strength training

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Conditions

The condition(s) this trial relates to.

cognitive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Ageing Brain health Cognition Cognitive performance Healthy ageing Longevity MEMORY Muscle strength Strength training effects

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • NuTraLab

    RECRUITING

    Vienna, State of Vienna, 1070, Austria

More trials for these conditions

Other studies related to the condition(s) this trial covers.