Could a common supplement help liver patients in intensive care?
NCT ID NCT07642076
First seen Jun 27, 2026 · Last updated Jul 22, 2026 · Updated 2 times
Summary
This study looks at whether adding L-carnitine, a natural substance, to standard care can improve outcomes for critically ill adults with liver disease in the ICU. About 58 participants with conditions like liver failure or severe infections will be enrolled. Researchers will track key lab tests such as kidney and liver function to see if L-carnitine helps.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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About 58 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jun 2026
An estimate. Start dates often move.
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age more than 18 years old * male or female with confirmed liver disease admitted to intensive care unit, including: * Acute-on-chronic liver failure (ACLF) * Hepatic encephalopathy * spontaneous bacterial peritonitis (SBP) * variceal bleeding * fulminant hepatitis * Hepatorenal syndrome * Ascites * Etc Exclusion Criteria: * Age of less than 18 years old * Pregnancy or Lactation * patients have seizure * patient on warfarin
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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National liver institute
RECRUITINGMenoufia, Egypt
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