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Experimental drug KZR-261 tested in patients with advanced cancers

NCT ID NCT05047536

First seen Jan 03, 2026 · Last updated May 22, 2026 · Updated 26 times

Summary

This early-phase study tested a new drug called KZR-261 in 61 people with advanced solid tumors (like melanoma, colorectal, or prostate cancer) that had stopped responding to standard treatments. The main goals were to check the drug's safety, find the best dose, and see if it could shrink tumors. The study was stopped early, so results are limited, but it aimed to control the disease rather than cure it.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Cedars Sinai Medical Center

    Los Angeles, California, 90048, United States

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

  • Fox Chase Cancer Center

    Philadelphia, Pennsylvania, 19111, United States

  • Fred Hutchinson Cancer Center

    Seattle, Washington, 98109, United States

  • Henry Ford Health System

    Detroit, Michigan, 48202, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • START (South Texas Accelerated Research Therapeutics)

    San Antonio, Texas, 78229, United States

  • Sara Cannon Research Institution (SCRI) - Tennessee Oncology Nashville

    Nashville, Tennessee, 37203, United States

  • University Hospitals - Cleveland Medical Center

    Cleveland, Ohio, 44106, United States

  • University of California Los Angeles

    Los Angeles, California, 90095, United States

  • Virginia Cancer Specialists (VCS)

    Fairfax, Virginia, 22031, United States

  • Winship Cancer Institute of Emory University

    Atlanta, Georgia, 30322, United States

Conditions

Explore the condition pages connected to this study.