Immune cell therapy shows promise for tough lupus kidney cases
NCT ID NCT05938725
First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 26 times
Summary
This early-stage study tests a new treatment called KYV-101 for people with lupus nephritis that hasn't improved with standard therapies. The treatment uses a patient's own immune cells, modified to target and destroy harmful B cells that drive the disease. The study aims to check safety and whether it can improve kidney function in 6 adults.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Northwell Health
Great Neck, New York, 11021, United States
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Ohio State University Wexner Medical Center
Columbus, Ohio, 43210, United States
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Stanford University Medical Center
Palo Alto, California, 94305, United States
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University of Colorado
Denver, Colorado, 80045, United States
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University of Massachusetts Worcester
Worcester, Massachusetts, 01655, United States
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
Conditions
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