Experimental CAR t therapy takes aim at tough lupus kidney cases
NCT ID NCT05938725
First seen Nov 01, 2025 · Last updated Apr 23, 2026 · Updated 20 times
Summary
This early-phase study tests a treatment called KYV-101, made from a patient's own immune cells, for people with lupus nephritis that hasn't improved with standard care. The goal is to see if it's safe and can help control kidney inflammation. Only 6 adults with active lupus kidney disease are taking part.
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This is a summary of
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Northwell Health
Great Neck, New York, 11021, United States
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Ohio State University Wexner Medical Center
Columbus, Ohio, 43210, United States
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Stanford University Medical Center
Palo Alto, California, 94305, United States
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University of Colorado
Denver, Colorado, 80045, United States
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University of Massachusetts Worcester
Worcester, Massachusetts, 01655, United States
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
Conditions
Explore the condition pages connected to this study.