Red ginseng capsules tested on 900 people for Anti-Aging benefits
NCT ID NCT05592093
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether Korean red ginseng capsules can reduce oxidative stress in 900 healthy middle-aged and older adults (40–75 years old). Participants took either the ginseng or a placebo for 12 weeks. The main goal was to see changes in a blood marker called MDA, which is linked to cell damage and aging.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Korean red ginseng capsule
- What this could lead to
- If it works, this could point toward a natural supplement to help reduce oxidative stress and support healthy aging in middle-aged and older adults.
- What could go wrong
- This is a completed Phase 2/3 trial, but it only measured blood markers (like MDA) rather than actual health outcomes. The effect may be small or not translate to real-world benefits.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2/3
Runs two stages together: whether the treatment works, then large-scale confirmation.
- Participants
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900 people
The number who actually took part.
- Started
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Mar 2023
- Finished
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Dec 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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40 to 75 years
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. 40-75 years old, male or female, Han nationality; 2. There was no history of major chronic disease or clinically active disease within 3 months before the study, including any cardiovascular, cerebrovascular, lung, kidney, liver, endocrine, digestive tract, nervous system or metabolic disease; Inflammation, psychosis, AIDS, tumor or traumatic injury, etc., and the disease history that the researcher judges to have an impact on the study; 3. According to the sub-health status evaluation questionnaire (shsq-25), ≥ 35 points can be judged as sub-health; 4. Agree to have no family planning or sperm donation plan during the trial and within 6 months after the end of the trial and voluntarily take effective contraceptive measures (avoid using contraceptives); 5. Cohabitants included only one subject; Those who sign the informed consent shall fully understand the test content, process and possible adverse reactions, and be able to communicate well with the investigator. Exclusion Criteria: 1. Those who need to take medicine (traditional Han Chinese medicine, western medicine, biological medicine) due to any major chronic disease or clinically active disease within 3 months before the study; 2. Obesity population (BMI index) (kg / m2) BMI ≥ 28KG / m2; Low body weight population (BMI index) (kg / m2) BMI \< 18.5kg/m2; 3. Vegetarians within 3 months before the study; 4. Those who took other antioxidant health products within 3 months before the study (vitamin health products or supplements; zinc and selenium health products or supplements; superoxide dismutase (SOD) health products; health products containing grape seeds, lycopene, flavonoids, astaxanthin, propolis, squalene, nicotinamide nucleoside, omega-3 or omega-6, etc.); 5. Those who took (or used) microecological regulators within 3 months before the study; 6. Those who drank more than 200ml of coffee per day (converted as pure coffee) within 3 months before the study; 7. Those who are known to be allergic to red ginseng ingredients, or who have a specific history of allergy (asthma, measles, eczema, etc.), or allergic constitution (such as those who are allergic to two or more drugs, food such as milk and pollen), or who have a history of food, drug hypersensitivity or allergic reaction judged by other researchers to have clinical significance; 8. Alcoholics (drinking more than 14 standard units per week. 1 standard unit contains 14g alcohol, such as 360ml beer or 45ml spirit with 40% alcohol or 150ml wine), or those with positive breath test within 3 months before the study; 9. Those who smoked more than 10 cigarettes per day in the 3 months before the study; 10. Those who have participated in or are participating in other clinical trials within 3 months before the study; 11. The investigator considered that there were other patients who were not suitable to participate in this study.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Beijing Obstetrics and Gynecology Hospital Affiliated to Capital Medical University
Beijing, Beijing Municipality, 100026, China
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Foshan Fuxing Changcheng Hospital
Foshan, Guangdong, 528031, China
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Nanchang Hongdu Hospital of TCM
Nanchang, Jiangxi, 330006, China
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Renji Hospital Affiliated to Shanghai Jiaotong University
Shanghai, Shanghai Municipality, 200127, China
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