New knee implant aims for better pain relief and mobility
NCT ID NCT05197036
First seen Feb 01, 2026 · Last updated Jun 19, 2026 · Updated 24 times
Summary
This study follows 299 people who received Smith+Nephew's porous total knee system to replace worn-out knee joints due to arthritis. The goal is to see if the implant reduces pain, improves movement, and lasts at least two years without needing revision. Participants are either getting the implant now or have already received it in the past year.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Columbia University
New York, New York, 10032, United States
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Concordia Joint Replacement Group
Winnipeg, Manitoba, R2K2M9, Canada
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Duke Health
Morrisville, North Carolina, 27560, United States
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Emory Orthopaedics and Spine Hospital
Atlanta, Georgia, 30084, United States
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Erlanger Health
Chattanooga, Tennessee, 37403, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Medical Center Leeuwarden
Leeuwarden, Leeuwarden, 8934, Netherlands
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Medical University of South Carolina
Charleston, South Carolina, 29425, United States
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NYU Langone Health Orthopedic Hospital
New York, New York, 10016, United States
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Oregon Health & Science University
Portland, Oregon, 97239, United States
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Sint Maartenskliniek
Ubbergen, Ubbergen,, 6574, Netherlands
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St George and Sutherland Centre for Clinical Orthopaedic Research
Sydney, New South Wales, Australia
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Syracuse Orthopedic Specialists
East Syracuse, New York, 13057, United States
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The Avenue Hospital
Windsor, Victoria, 3181, Australia
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The Core Institute
Novi, Michigan, 48374, United States
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UTHealth
Houston, Texas, 77401, United States
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Umeå University Hospital
Umeå, Umeå, 90737, Sweden
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University of Wisconsin
Madison, Wisconsin, 52718, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Porous Total Knee Arthroplasty System (titanium knee implant)
What this could lead to
If successful, this could confirm that the porous knee implant provides lasting pain relief and improved mobility for people with severe knee arthritis.
What could go wrong
This is an observational follow-up study, not a randomized trial, so results may not prove superiority over other implants. Some patients may still need revision surgery or experience complications.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.