New knee implant aims to make patients forget they have a replacement
NCT ID NCT05459948
First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 29 times
Summary
This study is testing a new knee implant called the GMK SpheriKA, placed using a special alignment technique. The goal is to see if patients can forget they have an artificial joint in everyday life. Researchers will follow 281 adults aged 18 to 80 who need a first-time total knee replacement. They will measure how natural the knee feels and how well it works over time.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Centre de l'Arthrose
RECRUITINGMérignac, France
Contact
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Clinique de l'Union
RECRUITINGSaint-Jean, 31240, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Gelenkzentrum Winterthur
RECRUITINGWinterthur, Switzerland
Contact
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Humanitas Castelli
RECRUITINGBergamo, Italy
Contact
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
GMK SpheriKA knee prosthesis
What this could lead to
If it works, this could mean a more natural-feeling knee replacement that patients barely notice in daily life.
What could go wrong
This is an observational post-market study, not a randomized trial. Results may not apply to all patients, and some may still feel the implant or have complications.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.