New knee implant aims to make patients forget they have a replacement

NCT ID NCT05459948

Recruiting now Symptom relief Sponsor: Medacta International SA Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a new knee implant called the GMK SpheriKA, placed using a special alignment technique. The goal is to see if patients can forget they have an artificial joint in everyday life. Researchers will follow 281 adults aged 18 to 80 who need a first-time total knee replacement. They will measure how natural the knee feels and how well it works over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: GMK SpheriKA knee prosthesis
What this could lead to: If it works, this could mean a more natural-feeling knee replacement that patients barely notice in daily life.
What could go wrong: This is an observational post-market study, not a randomized trial. Results may not apply to all patients, and some may still feel the implant or have complications.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

arthropathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ARTHROPATHY KNEE REPLACEMENT

Contacts and locations

Locations

Centre de l'Arthrose
RECRUITING

Mérignac, France
Clinique de l'Union
RECRUITING

Saint-Jean, 31240, France
Gelenkzentrum Winterthur
RECRUITING

Winterthur, Switzerland
Humanitas Castelli
RECRUITING

Bergamo, Italy

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