Which nerve block eases knee replacement pain best?
NCT ID NCT07040709
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested two types of nerve blocks—adductor canal block and suprainguinal fascia iliaca block—to see which controls pain better after total knee replacement. 86 adults having knee replacement under spinal anesthesia were randomly assigned to one block. Researchers measured pain scores and opioid use in the first 24 hours after surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- nerve block (adductor canal block or suprainguinal fascia iliaca plane block)
- What this could lead to
- If one block proves better, it could improve pain management and reduce opioid use after knee replacement surgery.
- What could go wrong
- This is a small, completed study. Results may not apply to all patients, and neither block may be clearly superior.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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86 people
The number who actually took part.
- Started
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Jun 2025
- Finished
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Mar 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients aged between 18 and 75 years * Patients classified as ASA I, II, or III based on physical status * Patients scheduled for total knee arthroplasty under spinal anesthesia Exclusion Criteria: * Patients with chronic pain conditions. * Patients with a history of allergy to opioids or local anesthetics. * Patients with psychiatric disorders that may impair cooperation. * Patients with bleeding disorders or those using anticoagulant therapy. * Patients unwilling to participate voluntarily in the study.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Tokat Gaziosmanpasa University
Tokat Province, ABD Veya Kanada'daysanız Lütfen Seçin..., 60100, Turkey (Türkiye)
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