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Which nerve block keeps you moving after knee surgery?

NCT ID NCT07739108

Symptom relief Sponsor: Bursa Yuksek Ihtisas Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 31, 2026 · Last updated Aug 04, 2026 · Updated 2 times

Summary

This trial compares two ultrasound-guided nerve blocks for pain control after total knee replacement. The goal is to see if one block preserves leg muscle strength better, allowing earlier movement, while providing similar pain relief. Sixty adults scheduled for knee replacement will receive one of the two blocks, and their pain and muscle strength will be measured over 48 hours.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Two nerve blocks: suprainguinal fascia iliaca block (S-FIB) and adductor canal block (ACB), both ultrasound-guided, compared for postoperative pain control.
What this could lead to
If one block proves better, it could improve recovery after knee replacement by reducing pain while helping patients move sooner.
What could go wrong
This is a small, early-stage trial, so results may not apply to all patients. Nerve blocks carry risks like infection or nerve damage, though rare.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Sep 2027

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

45 to 100 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * ASA Physical Status I, II, or III * Scheduled for elective unilateral primary total knee arthroplasty * Able to understand and operate the PCA device * Written informed consent provided Exclusion Criteria: * Pre-existing lower-extremity neurological deficit or motor weakness (e.g., severe diabetic neuropathy) * Chronic opioid use (\>30 mg oral morphine equivalents/day for \>3 months) * Infection at the block site or systemic sepsis * Coagulopathy or bleeding diathesis * Allergy to local anesthetics or study medications * Revision TKA or bilateral knee procedures * Cognitive impairment or inability to perform mobility/pain assessments

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Arthroplasty Arthroplasty, replacement, knee Knee osteoarthritis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

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