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Why do legs get weaker after knee replacement? new study digs in

NCT ID NCT03051984

First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 18 times

Summary

This study examined why leg muscles shrink and weaken after total knee replacement surgery. Researchers measured muscle fiber size and strength in 23 people with knee osteoarthritis before and after surgery. The goal was to understand the biological reasons behind muscle loss, which can slow recovery, and to find ways to prevent it in the future.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Vermont College of Medicine

    Burlington, Vermont, 05405, United States

Conditions

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