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AI-Powered knee rehab could replace surgery for common injuries

NCT ID NCT07423819

Symptom relief Sponsor: Peking University Third Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new digital system that uses wearable sensors, cameras, and AI to guide people through knee rehab exercises at home. It focuses on two common knee problems: ACL tears and patellar pain. 160 adults aged 18-50 will do strength, balance, and stretching exercises for 6 months, with regular check-ins to see if the digital approach improves knee function and pain better than standard remote rehab.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Digital rehabilitation system (wearable sensors, machine vision, AI) plus muscle strength, balance, and stretching exercises
What this could lead to
If successful, this could provide a more effective, technology-guided home rehab program for common knee injuries, potentially reducing the need for surgery or in-person therapy.
What could go wrong
This is an early-stage trial (not yet recruiting) with no prior results. The digital system's accuracy and patient adherence are unproven, and benefits over standard rehab are uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 160 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Mar 2026

An estimate. Start dates often move.

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 50 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age 18-50 years. 2. Clinical symptoms, signs, and MRI diagnosis confirming ACL rupture. 3. First-time unilateral ACL rupture. 4. Clinical symptoms, signs, and MRI diagnosis confirm patellofemoral cartilage injury. 5. Presence of at least one of the following manifestations: 1. Initially, unilateral knee presents with dull pain, soreness, or a sense of weakness, followed by increased knee pain predominantly located behind the patella. Pain worsens after exertion, with difficulty climbing up or down stairs, and alleviates or disappears after rest. The pain VAS score is ≤6 points. 2. Positive unilateral knee patellar grind test and/or positive patellar compression test and/or positive squat test. 6. Ability to understand and sign the informed consent form, voluntarily participate in the study, and cooperate with follow-up. Exclusion Criteria: 1. Body Mass Index (BMI) less than 18.5 or greater than 35 kg/m²; 2. Age greater than 50 years or less than 18 years; 3. History of knee surgery or presence of other conditions, such as tumors, rheumatoid arthritis, tuberculosis, etc.; 4. Severe cardiopulmonary dysfunction, neurological disorders, or other conditions unsuitable for exercise rehabilitation; 5. Pregnant or lactating women; 6. Individuals unwilling to undergo this treatment method.

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Conditions

The condition(s) this trial relates to.

Anterior Cruciate Ligament Injuries Patella Fracture patellofemoral pain syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anterior cruciate ligament injury Patellofemoral pain syndrome

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    4 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Beijing Jishuitan Hospital

    Beijing, China

  • Peking Union Medical College Hospital

    Beijing, China

  • Peking University People's Hospital

    Beijing, China

  • Peking University Third Hospital

    Beijing, China

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