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Knee surgery pain showdown: which technique wins?

NCT ID NCT03620136

Symptom relief Sponsor: Hospices Civils de Lyon Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compared two ways to manage pain after knee replacement surgery: a nerve block in the thigh (adductor channel block) versus injecting numbing medicine around the knee joint. 98 adults having their first knee replacement took part. The goal was to see which method reduced the need for morphine and eased pain better.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

98 people

The number who actually took part.

Started

Feb 2018

Finished

Nov 2019

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Major patients (≥18 years), * Having an American Society of Anesthesiology score (ASA) I to III * To benefit from first and unilateral prosthetic replacement surgery of knee under spinal anesthesia, * Having social security scheme, * Having received informed information and having signed informed consent Exclusion Criteria: * Pregnant women (diagnosis of interrogation), * Breastfeeding women * Patients under tutorship or curatorship, * Persons who can not receive sufficient information because of disturbances of superior functions or because of insufficient command of the French language according to the judgment of the investigator, * A history of chronic neuropathic pain in the leg to be operated on, * Patients who have undergone prior surgery on the knee to perform surgery, * Contra-indication to loco-regional anesthesia: known allergy to local anesthetics, * Contra-indication to the use of ROPIVACAINE: known hypersensitivity to the active substance or other amide-linked local anesthetics, hypovolemia * A morbid obesity (Body Mass Index (BMI)\> 40), * Severe renal insufficiency (Glomerular Filtration Rate (GFR) \<30mL / min), * Severe hepatic impairment (prothrombin rate PR \<50%), * Heart failure (left ventricular ejection fraction (LVEF)\<40%), * Transplanted patients, * A history of drug abuse, * The taking of chronic morphine for 6 months in systematic, * Any inability to understand visual scale, * An inability to walk pre-existing, * Participation in other interventional research, excluding physiological studies and other interventional research that does not interfere with the analysis of the primary endpoint (as determined by the investigator).

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Analgesic

Contacts and locations

Locations

  • Croix Rousse Hospital

    Lyon, 69004, France