One-shot knee gel aims to ease arthritis pain without surgery
NCT ID NCT05727371
First seen Feb 14, 2026 · Last updated May 24, 2026 · Updated 11 times
Summary
This study tests whether a single injection of a mix of platelet-rich plasma (from your own blood) and a gel-like substance can reduce pain and stiffness in people with moderate to severe knee osteoarthritis. About 280 adults with knee arthritis grade 3 or 4 will receive either the new combination, a standard gel, or a placebo. The goal is to see if the new mix works better and is safe.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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CHU Henri Mondor APHP
Créteil, France
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CHU Limoges
Limoges, France
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CHU Nantes Hôtel - Dieu
Nantes, France
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Centre Hospitalier Départemental Vendée
La Roche-sur-Yon, France
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Centre Hospitalier Lyon Sud
Lyon, France
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Centre Hospitalier Sud-Francilien
Corbeil-Essonnes, France
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Ch de Narbonne
Narbonne, France
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Clinique Medipole Garonne, Radiologie Interventionnelle 45 Rue Gironis
Toulouse, 31100, France
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Hopital Lapeyronie
Montpellier, 34295, France
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Hopital Le Bocage Chru
Dijon, DE, 21079, France
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Hopital Maison Blanche
Reims, 51092, France
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Hôpital Lariboisière
Paris, France
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Hôpital Saint-Antoine
Paris, France
Conditions
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