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Knee osteoarthritis relief: which therapy technique works better?

NCT ID NCT07402291

Symptom relief Sponsor: Riphah International University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compared two physical therapy techniques—Mulligan's Pain Release Phenomenon and Kaltenborn Mobilization—for knee osteoarthritis. 44 adults aged 40-65 with early knee osteoarthritis received either technique plus conventional exercises for 6 weeks. Researchers measured pain, stiffness, and range of motion to see which approach offered more relief.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Physical therapy techniques (Mulligan's Pain Release Phenomenon and Kaltenborn Mobilization) plus conventional exercises
What this could lead to
If one technique proves better, it could offer a more effective non-drug option for easing knee osteoarthritis symptoms.
What could go wrong
This is a small, completed trial with only 44 participants, so results may not apply to everyone. Both techniques are generally low-risk, but individual responses vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

44 people

The number who actually took part.

Started

Jun 2025

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age included between 40-65 years * NPRS pain rating above 3 * Both Genders * Diagnosed with Grade 1 and Grade 2 knee osteoarthritis * Unilateral knee pain * Pain for more than 3 months * Decrease range of motion Exclusion Criteria: * Age more than 60 years * Bilateral knee pain * Patellofemoral pain syndrome * Rheumatoid Arthritis * Fracture or ligamentous injury of lower extremity * Any trauma, burn, infection or tumor around the knee * Total knee replacement

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Knee osteoarthritis

Contacts and locations

Locations

  • SAP Rehab Center

    Lahore, Punjab Province, 54000, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.