New gel could ease knee pain without pills
NCT ID NCT07319728
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage study tests a new gel containing ketoprofen, applied to the skin, for people with knee osteoarthritis. The goal is to see if it reduces pain and improves knee function. Forty adults with knee osteoarthritis will be randomly assigned to receive the gel or a comparison treatment, and neither they nor the researchers will know who gets which.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 1
The first testing in people. Mainly checks safety and dose, usually in a small group.
- Participants
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40 people
The number who actually took part.
- Started
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May 2025
- Expected to finish
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Feb 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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45 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patient diagnosed with osteoarthritis in knee by: Full history taking Physical examination including (joint tenderness, swelling, crepitus and limitation of motion). Exclusion Criteria: * 1\. Patients with dual diagnosis 2. Patients have skin lesion or dermatologic disease in the treatment area
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Minia University
Minya, Minya Governorate, 11666, Egypt
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Other studies related to the condition(s) this trial covers.
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