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Mind over knee pain? study probes link between worry and osteoarthritis suffering

NCT ID NCT07609056

Knowledge-focused Sponsor: Fatih Sultan Mehmet Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Sep 02, 2026 · Updated 3 times

Summary

This observational study looks at 103 adults with knee osteoarthritis to see if repetitive negative thinking (rumination and worry) is linked to worse pain and disability, even when X-ray damage is similar. Participants fill out questionnaires about their thoughts, pain, and daily function. The goal is to understand why some people hurt more than others with the same joint damage, which could lead to treatments that address both mind and body.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could point toward adding psychological support to standard knee osteoarthritis care, potentially improving pain management without new drugs.
What could go wrong
This is an observational study, not a treatment trial. It only measures thoughts and pain at one time point, so it cannot prove that changing thinking reduces pain. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

103 people

The number who actually took part.

Started

Mar 2026

Finished

Jun 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adults presenting with knee pain to the orthopedic and traumatology outpatient clinic who are diagnosed with knee osteoarthritis based on radiographic evaluation will be enrolled in this observational study. Participants will undergo assessment of radiographic osteoarthritis severity, pain severity, functional limitation, rumination, and worry using validated clinical and psychological questionnaires.

Ages

18 to 80 years

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 years or older * Diagnosis of knee osteoarthritis confirmed by radiographic evaluation * Ability and willingness to provide informed consent * Ability to complete study questionnaires Exclusion Criteria: * Presence of comorbid conditions that may cause knee pain other than osteoarthritis * Analgesic medication use within the previous week * Cognitive impairment or psychiatric conditions that may interfere with questionnaire completion, including dementia, intellectual disability, or psychotic disorders

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee Pain rumination disorder Rumination Syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Osteo arthritis knee Rumination Worries; pain or disability

Contacts and locations

Locations

  • Fatih Sultan Mehmet Training and Research Hospital

    Istanbul, Atasehir, 34752, Turkey (Türkiye)

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