Which exercise routine wins for knee pain? new study puts two therapies Head-to-Head
NCT ID NCT07593599
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed study tested two different physical therapy programs in 84 adults aged 40-60 with grade II knee osteoarthritis. One group received the Macquarie injury management protocol (soft tissue work plus exercises), while the other did a targeted knee exercise program. Researchers measured pain, range of motion, and daily function to see which approach worked better.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- physical therapy (Macquarie injury management group protocol and targeted knee exercise program)
- What this could lead to
- If one approach proves better, it could point toward a more effective physical therapy routine for easing knee osteoarthritis symptoms.
- What could go wrong
- This is a small, completed trial with no blinding, so results may not apply broadly. Both interventions are exercises, so no major risks beyond typical muscle soreness.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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84 people
The number who actually took part.
- Started
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Apr 2025
- Finished
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May 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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40 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Both female and male subjects aged between 40 to 60 year 2. Diagnosed knee osteoarthritis, Grade II by Kellegren Lawrence. Exclusion Criteria: 1. Any surgical procedure done for lower extremity 2. Any infection 3. Post traumatic knee stiffness 4. Secondary knee osteoarthritis 5. Peripheral vascular disease.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Johar pain relief center ,Lahore
Lahore, Punjab Province, 54000, Pakistan
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