Knee surgery showdown: allograft vs autograft – which is better?
NCT ID NCT03932838
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is for adults who have had surgery to repair multiple torn knee ligaments at once. It compares two types of tissue grafts used in the surgery: one from a donor (allograft) and one from the patient's own body (autograft). The goal is to see how well the knee works and how stable it is after recovery, using special X-rays to measure looseness. The study does not offer a new treatment but aims to gather information to help doctors choose the best graft.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 80 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2017
- Expected to finish
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Jun 2035
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients operated for one-time allograft or autograft reconstruction of multiligamentous knee injury * \>18 years old Exclusion Criteria: * Neurological or vascular injury during trauma. * Fracture of the femur or both bones of the leg. * Ligamentous lesion on the contralateral knee. * History of surgery on the affected knee.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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CH de Versailles
RECRUITINGLe Chesnay, France
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