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A quick shave of knee fat may free stem-like cells to aid repair

NCT ID NCT07736716

Knowledge-focused Sponsor: Ankara City Hospital Bilkent Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 30, 2026 · Last updated Jul 31, 2026 · Updated 1 time

Summary

This study tests whether a brief, gentle shaving of the infrapatellar fat pad during knee arthroscopy can release cells that look like mesenchymal stem cells into the joint fluid. Researchers also check whether this procedure changes the activity of genes linked to inflammation and tissue repair. The trial involves adults with meniscal tears scheduled for knee surgery, comparing fluid samples taken before and right after the fat pad is shaved.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
controlled mechanical release of the infrapatellar fat pad
What this could lead to
If this works, it could point toward a simple way to boost the knee's own repair cells during routine surgery.
What could go wrong
This is a very early lab study with only 26 people. It measures cell counts and gene activity, not actual pain or function, so any benefit is uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

26 people

The number who actually took part.

Started

Jan 2024

Finished

Jan 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 55 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 18 and 55 years * Presence of knee pain * Meniscal tear confirmed by magnetic resonance imaging * Scheduled to undergo arthroscopic knee surgery * Provision of written informed consent to participate in the study Exclusion Criteria: * Requirement for emergency surgery * Open injury involving the knee * Severe anterior or posterior cruciate ligament injury causing substantial knee instability * Tibial eminence fracture * Osteochondral defect requiring surgical treatment * Planned open knee surgery * Suspected septic arthritis * Inflammatory arthritis * Suspected intra-articular tumor * Previous arthroscopic surgery on the same knee * Declining to participate in the study

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Conditions

The condition(s) this trial relates to.

Chronic Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Knee acute and chronic pain Knee arthroscopy surgery Meniscal tears

Contacts and locations

Locations

  • Ankara Bilkent City Hospital

    Ankara, Ankara, 06800, Turkey (Türkiye)

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