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Knee workouts may ease back pain, new study suggests

NCT ID NCT07337213

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether strengthening the knee muscles can reduce pain and improve posture in adults with chronic low back pain. 128 men aged 40-60 will do different knee exercises three times a week for 8 weeks. Researchers will measure changes in spine curvature, pain levels, and daily function.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
knee extensor exercises (open and closed kinetic chain)
What this could lead to
If successful, this could offer a simple, drug-free exercise option to reduce pain and disability in people with chronic low back pain.
What could go wrong
This is a small, early-stage trial with no blinding, so results may be biased. The exercises may not outperform standard back strengthening, and benefits might not apply to all back pain sufferers.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 128 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Feb 2026

An estimate. Start dates often move.

Expected to finish

Jun 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 60 years

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: I. Males aged 40 to 60 years, II. nonsmokers, III. with normal body mass index IV. of Saudi nationality, V. office workers, VI. suffering from chronic NLBP for 12 weeks or more with a moderate disability according to the Oswestry Disability Index (score of 21 - 40%) moderate activity level according to the Arabic version of the International Physical Activity Questionnaire short form . Exclusion Criteria: I. Previous spinal surgery, fracture, deformity, or disease. II. Neurological deficit and Lower limb deformity or fracture, or disease. III. Mental or psychological illness. The Arabic version of the Self-Reporting Questionnaire (SRQ-20) developed by the World Health Organization (WHO) to screen for common mental disorders such as depression and anxiety, uses a cut-off score to distinguish between individuals with and without significant psychological distress. A score of 7 or below is generally considered "normal", indicating no significant psychological distress (Al-Subaie et al., 1998). IV. Systematic chronic illnesses such as hypertension, cardiac and respiratory disorders, and diabetes mellitus.

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As listed by the trial registrant

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How to take part

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  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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  2. A doctor treating you

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