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New shot aims to stop bleeds in Tough-to-Treat hemophilia

NCT ID NCT06312475

First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 21 times

Summary

This study tests a medicine called KN057 to see if it can prevent bleeding episodes in people with hemophilia A or B who have developed inhibitors (antibodies that block standard treatment). About 53 participants will be randomly assigned to receive either KN057 injections regularly for a year or to first receive on-demand treatment for 6 months and then switch to KN057. The main goal is to count how many bleeding episodes occur in each group.

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Contacts and locations

Locations

  • Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences

    Tianjin, Tianjin Municipality, 300020, China

Conditions

Explore the condition pages connected to this study.