New shot may cut bleeding episodes in Tough-to-Treat hemophilia

NCT ID NCT06312475

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 20 times

Summary

This study tests a new medicine called KN057 to see if it can prevent bleeding episodes in people with hemophilia A or B who have developed inhibitors (antibodies that block standard treatment). About 53 men aged 12 to 70 will take part. Some will get KN057 regularly for a year, while others will first receive standard on-demand treatment for 6 months before switching to KN057. The main goal is to count how many bleeding episodes occur in each group.

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Contacts and locations

Locations

  • Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences

    Tianjin, Tianjin Municipality, 300020, China

Conditions

Explore the condition pages connected to this study.