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New drug KK2260 enters first human trials for Hard-to-Treat cancers

NCT ID NCT06248411

Recruiting now Disease control Sponsor: Kyowa Kirin Co., Ltd. Source: ClinicalTrials.gov ↗

First seen Feb 22, 2026 · Last updated May 22, 2026 · Updated 14 times

Summary

This study tests a new drug called KK2260 in people with advanced or metastatic solid tumors (cancers that have spread). It is the first time this drug is being used in humans. The study has three parts: first, finding the safest dose; then testing different dosing schedules in esophageal and head & neck cancers. About 189 adults who have tried other treatments without success may join. The goal is to check safety and see if the drug shrinks tumors.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Aichi Cancer Center Hospital

    RECRUITING

    Nagoya, Aichi-ken, 464-8681, Japan

  • Hiroshima University Hospital

    NOT_YET_RECRUITING

    Hiroshima, Hiroshima, 734-8551, Japan

  • Kanagawa Cancer Center

    RECRUITING

    Yokohama, Kanagawa, 241-8515, Japan

  • Kobe University Hospital

    RECRUITING

    Kobe, Hyōgo, 650-0017, Japan

  • Kumamoto University Hospital

    NOT_YET_RECRUITING

    Kumamoto, Kumamoto, 860-8556, Japan

  • Kyushu Cancer Center

    RECRUITING

    Fukuoka, 811-1347, Japan

  • National Cancer Center Hospital

    RECRUITING

    Chuo-ku, Tokyo, 104-0045, Japan

  • National Cancer Center Hospital East

    RECRUITING

    Kashiwa, Chiba, 277-8577, Japan

  • Osaka International Cancer Institute

    RECRUITING

    Osaka, 540-0008, Japan

  • Saitama Cancer Center

    RECRUITING

    Shinden, Saitama, 362-0806, Japan

  • Shizuoka Cancer Center

    RECRUITING

    Nagaizumi-cho, Shizuoka, 411-8777, Japan

  • The Cancer Institute Hospital of JFCR

    RECRUITING

    Koto-ku, Tokyo, 135-8550, Japan

  • Tohoku University Hospital

    NOT_YET_RECRUITING

    Sendai, Miyagi, 980-8574, Japan

Conditions

Explore the condition pages connected to this study.

ADVANCED OR METASTATIC SOLID TUMORS ADVANCED OR METASTATIC SOLID TUMORS