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New blood test could predict kidney transplant rejection before it happens

NCT ID NCT04727788

Diagnosis Sponsor: Verici Dx Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a blood test that looks at gene activity to predict the risk of kidney transplant rejection. Researchers will follow 550 kidney transplant recipients to see if the test can identify those at risk for early rejection or long-term damage. The goal is to help doctors intervene sooner and improve transplant outcomes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this blood test could help doctors identify kidney transplant patients at high risk for rejection early, allowing for personalized treatment.
What could go wrong
This is an observational study, not a treatment trial. The test may not be accurate enough for widespread use, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 550 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2021

Expected to finish

Dec 2025

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Kidney or kidney/pancreas transplant patients

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Individual Recipients of living or deceased donor kidney transplant 2. Age: ≥ 18 ≤ 80 3. The subject must be able to comprehend and sign an approved informed consent form Exclusion Criteria: 1. Recipients of multiple organ transplant, except kidney-pancreas multiple transplant 2. Subjects who are currently participating in a therapeutic clinical trial for transplant rejection 3. HIV or Hepatitis C positive patients 4. Persons who are known to be pregnant

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Conditions

The condition(s) this trial relates to.

transplant rejection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Kidney transplant rejection

Contacts and locations

Locations

  • Bologna University

    Bologna, Italy

  • Brescia University

    Brescia, Italy

  • CHU Grenoble Alpes Health Center

    Grenoble, France

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

  • Henry Ford

    Detroit, Michigan, 48202, United States

  • Northwestern University

    Evanston, Illinois, 60611, United States

  • University Hospital Vall d'Hebron, Barcelona

    Barcelona, Spain

  • University of Illinois at Chicago

    Chicago, Illinois, 60612, United States

  • University of Maryland

    Baltimore, Maryland, 21201, United States

  • University of Nebraska Medical Center

    Omaha, Nebraska, 68198, United States

  • University of Pittsburgh

    Pittsburgh, Pennsylvania, 15261, United States

  • University of Washington

    Seattle, Washington, 98195, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States

More trials for these conditions

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