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New drug combo could slash kidney transplant wait times for Hard-to-Match patients

NCT ID NCT05017545

First seen Feb 28, 2026 · Last updated May 23, 2026 · Updated 13 times

Summary

This study tests whether two drugs, carfilzomib and belatacept, can lower immune sensitivity in highly sensitized kidney transplant candidates. These patients often wait over 5 years for a compatible donor. The goal is to make more donors acceptable and speed up transplantation. The trial involves 21 participants and focuses on safety and effectiveness.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Duke Transplant Center, Duke University Medical Center

    Durham, North Carolina, 27710, United States

Conditions

Explore the condition pages connected to this study.