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Which surgery is safer for a single kidney with stones? a Head-to-Head trial

NCT ID NCT07730892

Disease control Sponsor: Mansoura University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time

Summary

This trial compares two surgical techniques—percutaneous nephrolithotomy (PCNL) and retrograde intrarenal surgery (RIRS)—for removing kidney stones up to 3 cm in people who have only one functioning kidney. The goal is to see which approach clears more stones with fewer complications and better preserves kidney function. Adults with a solitary kidney and stones of 3 cm or smaller are eligible to participate.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
two surgical procedures: percutaneous nephrolithotomy (PCNL) and retrograde intrarenal surgery (RIRS)
What this could lead to
If one procedure proves safer or more effective, it could become the preferred option for people with a solitary kidney who need stone removal.
What could go wrong
This is a non-randomized study, so results may be biased. The sample size is modest, and findings may not apply to all stone sizes or patient types.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 83 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2024

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with anatomical or functional solitary kidney. * Renal stones ≤ 3 cm in largest diameter- as measured by non-contrast spiral CT * Age ≥ 18 years. Exclusion Criteria: * Patients who did not meet the above criteria. * bleeding diathesis or those on anticoagulant therapy. * concomitant pathology as ureteric stricture or renal congenital anomalies .

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Conditions

The condition(s) this trial relates to.

nephrolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Renal stones

Contacts and locations

Locations

  • Urology and Nephrology center , Mansoura University

    Al Mansurah, Dakahlia Governorate, 35516, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.