Can common heart drugs also shield the kidneys?
NCT ID NCT07685054
First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time
Summary
This study looks at whether two different combinations of blood pressure and cholesterol medications can help protect kidney function in people with both high blood pressure and high cholesterol. Researchers will track changes in urine protein levels and other kidney markers over 24 weeks. The goal is to see if these drug combinations offer extra kidney benefits beyond controlling blood pressure and cholesterol.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- fimasartan, atorvastatin, and ezetimibe
- What this could lead to
- If successful, this could show that these drug combinations help protect kidney function in people with high blood pressure and high cholesterol.
- What could go wrong
- This is an observational study, not a controlled trial, so it cannot prove cause and effect. Results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 12,700 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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Aug 2029
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients diagnosed with essential hypertension and primary hypercholesterolemia
- Ages
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19 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Those who are briefed about the clinical trial objectives and methods, and express their consent to participate in the trial by signing a written consent on the use of their personal information. * Patients diagnosed with essential hypertension and primary hypercholesterolemia. * Patients scheduled to receive either fimasartan plus atorvastatin or fimasartan plus atorvastatin plus ezetimibe. Exclusion Criteria: * Patients who received concomitant administration of fimasartan and atorvastatin within 4 weeks prior to baseline. * Patients with any contraindication to fimasartan, atorvastatin, or ezetimibe as specified in the approved product labeling. * Patients who have received investigational or study drugs from another clinical trial or research study within 12 weeks prior to baseline. However, participation in non-interventional observational studies is permitted. * Patients considered unsuitable for study participation at the discretion of the principal investigator or sub-investigator.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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