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Can a simple MRI spot kidney trouble early? new study aims to find out

NCT ID NCT06884410

Knowledge-focused Sponsor: Mario Negri Institute for Pharmacological Research Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study is testing how consistently kidney MRI scans work on standard 1.5T machines. It involves 48 healthy volunteers who will undergo repeated MRI scans to measure kidney size, blood flow, and oxygen levels. The goal is to make kidney MRI a reliable tool for diagnosing disease without needles or contrast dyes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help standardize kidney MRI as a reliable tool for detecting and monitoring kidney disease without needles or contrast dyes.
What could go wrong
This is a small, early-stage study in healthy people only, so results may not apply to patients with kidney disease. It does not test any treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 48 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2025

Expected to finish

Apr 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Provision of written informed consent prior to any study specific procedures * Male and female subjects aged \[18-70\] years * Office SBP values \< 140 mmHg and DBP values ≤ 90 mmHg, under no antihypertensive therapy * Normal renal function defined as: estimated glomerular filtration rate \[eGFR\] ≥ 60mL/min/1.73m2 (using CKD-EPI Creatinine Equation) * Negative result upon urine testing for haematuria or proteinuria. Exclusion Criteria: * Previous enrollment in the present substudy * Contraindications to MRI including caustrophobia, pregnancy, cardiac pacemakers or other MRI-incompatible prostheses * Ongoing therapy (e.g. for diabetes, dyslipidemia, or any acute disease) * Past or current oncological pathology

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Multiparametric mri

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    4 sites in 4 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Aarhus University Hospital

    NOT_YET_RECRUITING

    Aarhus, 8200, Denmark

  • Clínica Universidad de Navarra

    NOT_YET_RECRUITING

    Pamplona, Navarre, 31008, Spain

  • IRCCS Azienda Ospedaliero-Universitaria di Bologna

    RECRUITING

    Bologna, BO, 40138, Italy

  • University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University

    NOT_YET_RECRUITING

    Mannheim, 68197, Germany

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