New gel could end the ouch of sensitive teeth
NCT ID NCT06464939
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a gel called KH001 to see if it can safely provide long-term relief for sensitive teeth. 120 adults with tooth sensitivity received three applications of the gel or a placebo. Researchers measured pain responses to air and touch to see if the gel worked better than a dummy treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
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120 people
The number who actually took part.
- Started
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Oct 2024
- Finished
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Dec 2025
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Is at least 18 years old by the time of the screening visit * Is in good general health as determined by the investigator * Has at least 2 non-adjacent teeth and is diagnosed with hypersensitive Exclusion Criteria: * Is allergic to the active drug substance or other excipients used in the investigational product * Has any history of alcohol or drug abuse * Has received any treatment related to dentin hypersensitivity within 8 weeks prior to the screening visit * Is jedged by the investigator as ineligible for participation for other reasons
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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ADA Forsyth
Cambridge, Massachusetts, 02142, United States
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Forsyth Institute
Cambridge, Massachusetts, 02142, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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