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Ketone supplements may shield your body from too much salt

NCT ID NCT05545501

First seen Nov 15, 2025 · Last updated Jun 19, 2026 · Updated 26 times

Summary

This study tests whether taking a ketone supplement can prevent the negative effects of eating too much salt, like high blood pressure and kidney strain. Researchers will give 35 healthy young adults either a high-salt diet with a ketone supplement or a placebo, then measure changes in blood pressure, blood vessel function, and kidney health. The goal is to find a simple way to reduce the health risks of a high-salt diet without requiring people to change their eating habits.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Indiana University, School of Public Health

    RECRUITING

    Bloomington, Indiana, 47405, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ketone supplement (beta-hydroxybutyrate)

What this could lead to

If it works, this could point toward a simple supplement to help counteract the harmful effects of a high-salt diet on blood pressure and kidney health.

What could go wrong

This is a small, early-stage study with only 35 participants, so results may not apply to everyone. It's also a short-term trial, so long-term benefits or risks are unknown.

Conditions

The condition(s) this trial relates to.

hypertensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.