Could a ketone drink boost exercise in heart failure patients?
NCT ID NCT06937320
First seen Nov 01, 2025 · Last updated Jun 20, 2026 · Updated 40 times
Summary
This study tests whether a ketone drink can help people with a type of heart failure (HFpEF) exercise more. Twenty participants will take either the ketone drink or a placebo for 8 weeks, then switch. The main goal is to see if the drink improves exercise capacity measured by a stress test.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Duke University
Durham, North Carolina, 27710, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ketone drink (KetoneIQ)
What this could lead to
If it works, this could point toward a simple dietary supplement to help people with heart failure exercise more easily.
What could go wrong
This is a small, early-phase study with only 20 people, so results may not apply to everyone. The drink may cause side effects or show no benefit over placebo.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.