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Could a ketone drink curb binge and restrict urges?

NCT ID NCT05507008

Symptom relief Sponsor: University of California, San Diego Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Aug 04, 2026 · Updated 2 times

Summary

This pilot study tests whether a ketone drink can help people with anorexia or bulimia by reducing the drive to binge or restrict food. Forty participants will take the drink twice daily for two weeks, and researchers will measure changes in eating behaviors, mood, and brain activity. The goal is to see if this supplement offers a safe way to ease symptoms.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
ketone drink (BHB supplement)
What this could lead to
If it works, this could point toward a simple supplement to help reduce the urge to restrict or binge in eating disorders.
What could go wrong
This is a very small pilot study with only 40 people, so results may not apply widely. It is also early-stage, so the supplement may not work better than placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

38 people

The number who actually took part.

Started

Oct 2022

Finished

Jul 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Must currently meet DSM-5 criteria for Anorexia Nervosa, Bulimia Nervosa, or OSFED Anorexia or Bulimia Nervosa based on the MINI diagnostic interview 2. Be medically stable as assessed by a comprehensive medical and behavioral evaluation conducted by a study physician 3. English as primary spoken language. 4. Ability to respond to EMA questions up to 6x per day within 60 minutes of receiving the message. Exclusion Criteria: 1. Psychotic illness/other organic brain syndromes, dementia, somatization disorders or conversion disorders 2. Current substance abuse or dependence in the past 3 months 3. Physical conditions (e.g., diabetes mellitus, pregnancy) known to influence eating or weight 4. Medical conditions associated with ketoacidosis: type 1 diabetes mellitus, acute pancreatitis, alcoholic gastritis, peptic ulcer disease, hepatitis or Boerhaave syndrome (esophageal rupture) 5. History of significant head trauma 6. Indication of intellectual disability or autism spectrum disorder 7. Known allergy to any of the KenetikR drink components: D-beta-hydroxybutyric acid (D-BHB), Stevia, Monkfruit, Potassium Bicarbonate, Sodium Bicarbonate Potassium Sorbate or Taste Task Solutions: Sucrose, Potassium Chloride, Sodium bicarbonate.

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Conditions

The condition(s) this trial relates to.

anorexia nervosa bulimia nervosa

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anorexia nervosa Atypical anorexia nervosa Atypical bulimia nervosa Bulimia nervosa

Contacts and locations

Locations

  • University of California San Diego

    San Diego, California, 92121, United States

More trials for these conditions

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