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Could a High-Fat diet help tame PTSD? tiny german study tests feasibility

NCT ID NCT07415590

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Aug 14, 2026 · Updated 3 times

Summary

This study tests whether a medically supervised 12-week ketogenic diet is practical for 6 adults with PTSD in Germany. The main goal is to see if people can stick to the diet and complete the study. It is not designed to measure how well the diet works for PTSD symptoms, but it may provide clues for a larger future trial.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
ketogenic diet
What this could lead to
If this diet is feasible, it could point toward a new way to help manage PTSD symptoms.
What could go wrong
This is a very small, early feasibility study with only 6 people. It is not designed to prove the diet works for PTSD, and results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

6 people

The number who actually took part.

Started

Mar 2026

Finished

Aug 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Mental capacity to provide informed consent * Provides written confirmation of informed consent * Adults (18-65 years) * Verified PTSD diagnosis according to DSM 5-TR or ICD-11 * Currently living in Germany * High treatment motivation (score \> 7/10) * Consent to information sharing within study staff (release from medical confidentiality) * No medical or psychiatric contraindication Exclusion Criteria: * Pregnant or breastfeeding * Active alcohol or drug misuse * BMI \< 18.5 * Currently medicated with glucocorticoids, lithium, anticonvulsants, hypertension medication, glucose-lowering medications, or SGLT-2 inhibitor medications * Diagnosed with type 1 or type 2 diabetes * Diagnosed with severely impaired kidney function * Diagnosed with ESLD (End Stage Liver Disease) or ESRD (End Stage Renal Disease) * Follows a vegan diet * History of eating disorders * Acute or chronic suicidality * Acute or chronic self-injury behavior * Acute positive psychotic/manic symptomatology * Already following a ketogenic diet within the past 6 weeks * Any change to psychiatric medication regimen in past 6 weeks * Severe hypercholesterolemia (may represent genetic metabolic disorder) * Porphyria, heart failure, pancreatitis * Institutionally dependent individuals

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hochschulambulanz der Universität der Bundeswehr München

    München, Bavaria, 80803, Germany

  • LMU Klinikum (Klinik für Anästhesiologie)

    München, Bavaria, 81377, Germany

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