Could a High-Fat diet help tame PTSD? tiny german study tests feasibility
NCT ID NCT07415590
First seen Jun 25, 2026 · Last updated Aug 14, 2026 · Updated 3 times
Summary
This study tests whether a medically supervised 12-week ketogenic diet is practical for 6 adults with PTSD in Germany. The main goal is to see if people can stick to the diet and complete the study. It is not designed to measure how well the diet works for PTSD symptoms, but it may provide clues for a larger future trial.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- ketogenic diet
- What this could lead to
- If this diet is feasible, it could point toward a new way to help manage PTSD symptoms.
- What could go wrong
- This is a very small, early feasibility study with only 6 people. It is not designed to prove the diet works for PTSD, and results may not apply to everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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6 people
The number who actually took part.
- Started
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Mar 2026
- Finished
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Aug 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Mental capacity to provide informed consent * Provides written confirmation of informed consent * Adults (18-65 years) * Verified PTSD diagnosis according to DSM 5-TR or ICD-11 * Currently living in Germany * High treatment motivation (score \> 7/10) * Consent to information sharing within study staff (release from medical confidentiality) * No medical or psychiatric contraindication Exclusion Criteria: * Pregnant or breastfeeding * Active alcohol or drug misuse * BMI \< 18.5 * Currently medicated with glucocorticoids, lithium, anticonvulsants, hypertension medication, glucose-lowering medications, or SGLT-2 inhibitor medications * Diagnosed with type 1 or type 2 diabetes * Diagnosed with severely impaired kidney function * Diagnosed with ESLD (End Stage Liver Disease) or ESRD (End Stage Renal Disease) * Follows a vegan diet * History of eating disorders * Acute or chronic suicidality * Acute or chronic self-injury behavior * Acute positive psychotic/manic symptomatology * Already following a ketogenic diet within the past 6 weeks * Any change to psychiatric medication regimen in past 6 weeks * Severe hypercholesterolemia (may represent genetic metabolic disorder) * Porphyria, heart failure, pancreatitis * Institutionally dependent individuals
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hochschulambulanz der Universität der Bundeswehr München
München, Bavaria, 80803, Germany
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LMU Klinikum (Klinik für Anästhesiologie)
München, Bavaria, 81377, Germany
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Other studies related to the condition(s) this trial covers.
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