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New sedation combo could speed up endoscopy recovery

NCT ID NCT07423676

Symptom relief Sponsor: Zagazig University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a combination of ketamine and dexmedetomidine (Ketodex) works faster and safer than the usual propofol-midazolam for sedation during upper GI endoscopy. Fifty-two adults aged 21–60 will be enrolled. Researchers will measure how quickly patients reach the right sedation level, how fast they recover, and any side effects.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Ketamine and dexmedetomidine (Ketodex) compared to propofol and midazolam
What this could lead to
If Ketodex works better, it could offer a faster, safer sedation option for routine GI endoscopy.
What could go wrong
This is a small, early-stage trial with only 52 participants. Results may not apply to all patients, and side effects like nausea or blood pressure changes are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 52 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Mar 2026

An estimate. Start dates often move.

Expected to finish

May 2026

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients not more than 60 years old with BMI \< 35 kg/m2

Ages

21 to 60 years

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria * Patient acceptance * Adults aged 21-60 years. * Both sexes * BMI\<35 kg/m2 * ASA physical status :I\& II * Patients Undergoing Gastrointestinal endoscopy * Duration \<30mintues Exclusion Criteria: * • Known allergy to any of the study drugs * Unstable Cardiovascular disease * Moderate to severe respiratory diseases

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Sedation during gi endoscopy

How to take part

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  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

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