New sedation combo could speed up endoscopy recovery

NCT ID NCT07423676

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a combination of ketamine and dexmedetomidine (Ketodex) works faster and safer than the usual propofol-midazolam for sedation during upper GI endoscopy. Fifty-two adults aged 21–60 will be enrolled. Researchers will measure how quickly patients reach the right sedation level, how fast they recover, and any side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Ketamine and dexmedetomidine (Ketodex) compared to propofol and midazolam

What this could lead to

If Ketodex works better, it could offer a faster, safer sedation option for routine GI endoscopy.

What could go wrong

This is a small, early-stage trial with only 52 participants. Results may not apply to all patients, and side effects like nausea or blood pressure changes are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

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